Boc-Leu-Lys-Arg-AMC hydrochloride salt

CAS: 109358-47-6

Ref. 3D-FB110554

Product Information

• Name: Boc-Leu-Lys-Arg-AMC hydrochloride salt
• Synonyms: <span class="text-smallcaps">L</smallcap>-Argininamide, N-[(1,1-dimethylethoxy)carbonyl]-<smallcap>L</smallcap>-leucyl-<smallcap>L</span>-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, Boc-Leu-Lys-Arg-AMC, Boc-Leu-Lys-Arg-Amc Hydrochloride Salt, N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</smallcap>-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-<smallcap>L</span>-argininamide

Description

Boc-Leu-Lys-Arg-AMC is a synthetic substrate that has been used in a number of clinical studies to identify the serine proteases that are involved in autoimmune diseases. It is a synthetic peptide composed of the amino acid sequence found in soybean trypsin. The peptide was shown to have high salt tolerance and was able to be hydrolyzed by polyclonal antibodies with specificity for amyloid protein, suggesting it may be useful as a biochemical marker for Alzheimer's disease. Boc-Leu-Lys-Arg-AMC has also been shown to be an efficient substrate for collagenase, which is an enzyme that breaks down collagen and causes tissue damage. This property makes this compound useful as a proteolytic agent for the removal of unwanted scar tissue or other lesions from diseased organs. Boc-Leu-Lys-Arg-AMC also has an optimum pH level of 7.5 and is active against influenza

• Brand: Biosynth

Chemical properties

• Molecular weight: 672.82 g/mol
• Formula: C₃₃H₅₂N₈O₇
• Purity: Min. 95%