1-(1,3-Benzodioxol-5-ylmethyl)piperidin-4-amine dihydrochloride

CAS: 76167-58-3

Ref. 3D-FB116221

Product Information

• Name: 1-(1,3-Benzodioxol-5-ylmethyl)piperidin-4-amine dihydrochloride
• Synonyms: 1-Benzo[1,3]dioxol-5-ylmethyl-piper, Idin-4-Ylamine, 4-Piperidinamine, 1-(1,3-Benzodioxol-5-Ylmethyl)-

Description

1-(1,3-Benzodioxol-5-ylmethyl)piperidin-4-amine dihydrochloride (1,3BDMC) is a selective soluble guanylate cyclase inhibitor. It inhibits the production of nitric oxide and guanosine 3',5'-cyclic monophosphate in vascular smooth muscle cells. This drug is used as an anesthetic agent and has been shown to have beneficial effects in animal models of hypoxemia. 1,3BDMC has also been evaluated for use in treating embolic disorders such as thrombosis and pulmonary embolism. The drug has been found to be safe when administered intravenously or intraarterially but can cause necrosis when applied directly to the artery wall. The drug can also impair blood flow by constricting vessels and inhibiting platelet aggregation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 234.29 g/mol
• Formula: C₁₃H₁₈N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C13H18N2O2/c14-11-3-5-15(6-4-11)8-10-1-2-12-13(7-10)17-9-16-12/h1-2,7,11H,3-6,8-9,14H2
• InChI key: InChIKey=CHPNPFRWYMETGD-UHFFFAOYSA-N
• SMILES: NC1CCN(Cc2ccc3c(c2)OCO3)CC1