N-Boc-D-allylglycine
CAS: 170899-08-8
Ref. 3D-FB12005
| 1g | 136.00 € | ||
| 2g | 205.00 € | ||
| 5g | 406.00 € | ||
| 10g | 633.00 € | ||
| 25g | 1,134.00 € |
Product Information
- Boc-(R)-2-Allylglycine
- (R)-N-tert-Butoxycarbonyl-2-amino-4-pentenoic acid
- (2R)-2-[(tert-butoxycarbonyl)amino]pent-4-enoate
- (2R)-2-[(tert-butoxycarbonyl)amino]pent-4-enoic acid-N-cyclohexylcyclohexanamine (1:1)
- Boc-D-Allylglycine.DCHA
- Boc-D-Allylglycine
N-Boc-D-allylglycine is a peptidomimetic drug that inhibits caspase-3, an enzyme involved in apoptosis. This drug has been shown to inhibit the proteolytic activity of caspase-3 and thereby inhibit the induction of cell death by various stimuli. N-Boc-D-allylglycine is orally bioavailable and is metabolized into two active analogs: N-(2-(N′-(allyloxycarbonyl)-L-alanyl))glycine (NAGL) and N′-(2-(N′-(allyloxycarbonyl)-L-alanyl))glycinamide (NAG). These active analogs are potent inhibitors of caspase-3, with more than 100 times the potency of the parent compound. This compound also has a prodrug form, which can be hydrolyzed by esterases or glucuronidases to release the active form
Chemical properties
Technical inquiry about: 3D-FB12005 N-Boc-D-allylglycine
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