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5-Bromo-2-hydrazinopyridine
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5-Bromo-2-hydrazinopyridine

CAS: 77992-44-0

Ref. 3D-FB127191

1gDiscontinued
2gDiscontinued
5gDiscontinued
250mgDiscontinued
500mgDiscontinued

Discontinued product. For inquiries about similar products, please fill out our form or email us at .


Product Information

Name:
5-Bromo-2-hydrazinopyridine
Synonyms:
  • pyridine
  • 5-bromo-2-hydrazino-
  • 5-Brom-2-hydrazinylpyridin
  • 5-Bromo-2-hydrazinylpyridine
  • Pyridine, 5-bromo-2-hydrazinyl-
  • 2-Hydrazino-5-Bromopyridine
  • 5-Bromo-2-hydrazinepyridine
  • 5-Bromo-pyridin-2-yl)-hydrazine
Description:

5-Bromo-2-hydrazinopyridine is a potent anticancer drug that inhibits the synthesis of DNA and RNA. It is used for the treatment of acute promyelocytic leukemia. 5-Bromo-2-hydrazinopyridine has been shown to be active against cancer cells in culture and has demonstrated antitumor activity in vivo. The mechanism of action involves inhibition of DNA polymerase II, which is responsible for the synthesis of DNA. This leads to cell cycle arrest and apoptosis induction. 5-Bromo-2-hydrazinopyridine also binds to terminal alkynes, which are intermediates in the production of polymers that are implicated in carcinogenesis. It inhibits this process by binding to a critical site on the enzyme acetaldehyde dehydrogenase and thereby preventing its activation by acetaldehyde.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
188.03 g/mol
Formula:
C5H6BrN3
Purity:
Min. 95%
InChI:
InChI=1S/C5H6BrN3/c6-4-1-2-5(9-7)8-3-4/h1-3H,7H2,(H,8,9)
InChI key:
InChIKey=QYQLEYTXFMOLEI-UHFFFAOYSA-N
SMILES:
NNc1ccc(Br)cn1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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