tert-Butyl 4-bromo-1H-indole-1-carboxylate

CAS: 676448-17-2

Ref. 3D-FB139486

Product Information

• Name: tert-Butyl 4-bromo-1H-indole-1-carboxylate
• Synonyms: tert-butyl-4-bromo-1H-indole-1-carboxylate, Tert-Butyl 4-Bromoindole-1-Carboxylate

Description

tert-Butyl 4-bromo-1H-indole-1-carboxylate is a low temperature, synthetic compound that has been used to synthesize welwitindolinone derivatives. A novel functionalized tertiary alcohol was prepared by the alkylation of a tertiary amine with 2,4,6-trichlorobenzoyl chloride. The reaction proceeded smoothly at room temperature and afforded the desired product in good yield. The cyclization of this tertiary alcohol with an intramolecular nucleophile (cycloadduct) led to the formation of a bicyclic furan derivative. This reaction was stereoselective and gave high yields for both steps.

• Brand: Biosynth

Chemical properties

• Molecular weight: 296.16 g/mol
• Formula: C₁₃H₁₄BrNO₂
• Purity: Min. 95%
• InChI: InChI=1S/C13H14BrNO2/c1-13(2,3)17-12(16)15-8-7-9-10(14)5-4-6-11(9)15/h4-8H,1-3H3
• InChI key: InChIKey=ZGBNKNOAADXGOH-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)n1ccc2c(Br)cccc21