3-Bromoisoxazole-5-carboxylic acid

CAS: 6567-35-7

Ref. 3D-FB142755

Product Information

• Name: 3-Bromoisoxazole-5-carboxylic acid
• Synonyms: 5-Isoxazolecarboxylic acid, 3-bromo-

Description

3-Bromoisoxazole-5-carboxylic acid is an isoxazole that has bronchodilating properties. It has been shown to be a potent and selective inhibitor of the phosphodiesterase enzyme PDE4, which is involved in the breakdown of cAMP in airway smooth muscle. 3-Bromoisoxazole-5-carboxylic acid also inhibits the production of proinflammatory cytokines, such as IL-1β, IL-6, and TNFα. This agent has been shown to be well tolerated in humans with asthma or chronic obstructive pulmonary disease (COPD).

• Brand: Biosynth

Chemical properties

• Molecular weight: 191.97 g/mol
• Formula: C₄H₂BrNO₃
• Purity: Min. 95%
• InChI: InChI=1S/C4H2BrNO3/c5-3-1-2(4(7)8)9-6-3/h1H,(H,7,8)
• InChI key: InChIKey=YNIMFLBFJCGBQK-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(Br)no1