1-(4-Benzoyl-1-piperazinyl)-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]- 1,2-ethanedione

CAS: 864953-29-7

Ref. 3D-FB145114

Product Information

• Name: 1-(4-Benzoyl-1-piperazinyl)-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]- 1,2-ethanedione
• Synonyms: Fostemsavir, 1,2-Ethanedione, 1-(4-benzoyl-1-piperazinyl)-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-, 1-(4-Benzoyl-1-piperazinyl)-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]-1,2-ethanedione, Piperazine, 1-benzoyl-4-[[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-c]pyridin-3-yl]oxoacetyl]-, Rukobia, BMS 663068

Description

Fostemsavir is a drug that inhibits the life cycle of HIV-1 by binding to its reverse transcriptase (RT). It has been shown to be effective against resistant mutants and is not affected by other drugs. Fostemsavir can be used in combination with other antiretroviral drugs for the treatment of HIV-1 infection. It is an oral prodrug that undergoes first-pass metabolism and is converted to fostemsavir in the liver. Fostemsavir has shown long-term efficacy, which may be due to its ability to neutralize HIV-1 and inhibit viral replication. This drug does not bind to human cells because it does not have any affinity for proteins found in human cells, such as albumin or histones. Fostemsavir is an antibody that binds specifically to the gp41 protein on the surface of HIV-1, preventing it from attaching to host cells and infecting them with a new virus.

• Brand: Biosynth

Chemical properties

• Molecular weight: 583.49 g/mol
• Formula: C₂₅H₂₆N₇O₈P
• Purity: Min. 95%