2-Butylboronicacid

CAS: 88496-88-2

Ref. 3D-FB147174

Product Information

• Name: 2-Butylboronicacid
• Synonyms: sec-Butylboronic acid, (1-Methylpropyl)Boronic Acid

Description

2-Butylboronic acid is a boron-containing organic compound that is used in cross-coupling reactions to form carbon-carbon bonds. It is prepared by the reaction of 2-bromobenzene with sodium diboride in an ether solvent. The yields of this reaction are typically high, giving 99% yield in the case of a Suzuki coupling reaction. Mechanistic studies have shown that the alkylboronic acid catalyzes the coupling by donating a proton to the alkyl halide and then activating it for nucleophilic attack on an electrophile. The anion formed from 2-butylboronic acid can be either a chloride or triflate, depending on whether the electrophile is an organometallic or organocarbon reagent. The regiospecificity of 2-butylboronic acid has been studied using single-crystal x-ray diffraction. The ligands are typically carbox

• Brand: Biosynth

Chemical properties

• Molecular weight: 101.94 g/mol
• Formula: C₄H₁₁BO₂
• Purity: Min. 95%
• InChI: InChI=1S/C4H11BO2/c1-3-4(2)5(6)7/h4,6-7H,3H2,1-2H3
• InChI key: InChIKey=MACOIFNUPFKZEI-UHFFFAOYSA-N
• SMILES: CCC(C)B(O)O