3-Bromophthalic anhydride

CAS: 82-73-5

Ref. 3D-FB14788

Product Information

• Name: 3-Bromophthalic anhydride
• Synonyms: 1,3-Isobenzofurandione, 4-bromo-, 4-Bromo-1,3-dihydro-2-benzofuran-1,3-dione, 4-Bromo-1,3-isobenzofurandione, 4-Bromo-2-Benzofuran-1,3-Dione, 4-Bromo-Isobenzofuran-1,3-Dione, 4-Bromoisobenzofuran-1,3-Dione, NSC 508895, Phthalic anhydride, 3-bromo-

Description

3-Bromophthalic anhydride is a small-molecule drug that has been conjugated to proteins and peptides to target specific tissues. It inhibits the activity of ns3 protease, which is a key enzyme in the production of amyloid β-protein. 3-Bromophthalic anhydride has also shown potential as a fluorescent probe for cardiac imaging and as an inhibitor of chloride channels in the nervous system. The synthesis of 3-bromophthalic anhydride involves reacting anthracene with chlorine gas in the presence of polyvinyl chloride, followed by chlorination at the 3 position using thionyl chloride.

• Brand: Biosynth

Chemical properties

• Molecular weight: 227.01 g/mol
• Formula: C₈H₃BrO₃
• Purity: Min. 95%
• Color/Form: Solid
• InChI: InChI=1S/C8H3BrO3/c9-5-3-1-2-4-6(5)8(11)12-7(4)10/h1-3H
• InChI key: InChIKey=AQBFKBMMIDHCFS-UHFFFAOYSA-N
• SMILES: O=C1OC(=O)c2c(Br)cccc21