4-Bromo-6-methoxyquinoline

CAS: 42881-66-3

Ref. 3D-FB151033

Product Information

• Name: 4-Bromo-6-methoxyquinoline
• Synonyms: Quinoline, 4-Bromo-6-Methoxy-

Description

4-Bromo-6-methoxyquinoline is a quinoline derivative that has been used to identify the presence of iodides in biomolecules. The reactions of 4-bromo-6-methoxyquinoline with various amines have been studied and found to be dependent on the stereochemistry of the amine. In particular, 4-bromo-6-methoxyquinoline reacts with pipecolic acid (lactam) to form an acridone product, while it reacts with chiral amines to form a racemic mixture. This reaction is possible due to the fact that the quinoline moiety can act as an electrophile and nucleophile at different points in its structure. The synthesis of 4-bromo-6-methoxyquinoline has also been used as an example for the synthesis of taxol, which is a drug used for treating cancer.

• Brand: Biosynth

Chemical properties

• Molecular weight: 238.08 g/mol
• Formula: C₁₀H₈BrNO
• Purity: Min. 95%
• InChI: InChI=1S/C10H8BrNO/c1-13-7-2-3-10-8(6-7)9(11)4-5-12-10/h2-6H,1H3
• InChI key: InChIKey=HRFFYKLVLCFCQG-UHFFFAOYSA-N
• SMILES: COc1ccc2nccc(Br)c2c1