1-Boc-oxopiperzine

CAS: 76003-29-7

Ref. 3D-FB15258

Product Information

• Name: 1-Boc-oxopiperzine
• Synonyms: Tert-butyl-3-oxo-1-piperazinecarboxylate, Tert-Butyl 3-Oxopiperazine-1-Carboxylate, 3-Oxo-Piperazine-1-Carboxylic Acid Tert-Butyl Ester
• CAS: 76003-29-7

Description

Pi3kδ is a protein that plays an important role in the regulation of cell growth. 1-Boc-oxopiperzine, a novel inhibitor of pi3kδ, has been shown to inhibit cancer cell proliferation and induce apoptosis by inhibiting the production of purines. This drug also inhibits the metabolic enzyme in wild-type mice, which leads to a reduced level of purines. The pharmacodynamics of 1-Boc-oxopiperzine was studied using immunoassays and biochemical assays on deficient mice. The results showed that this drug could inhibit tumor growth and had anti-tuberculosis activity in mice. Further research into the mechanism of action revealed that 1-Boc-oxopiperzine inhibits the production of enzymes involved in purine metabolism, such as pyridone oxidoreductase and imidazole synthase.

• Brand: Biosynth

Chemical properties

• Molecular weight: 200.24 g/mol
• Formula: C₉H₁₆N₂O₃
• Purity: Min. 95%
• InChI: InChI=1S/C9H16N2O3/c1-9(2,3)14-8(13)11-5-4-10-7(12)6-11/h4-6H2,1-3H3,(H,10,12)
• InChI key: InChIKey=FCMLWBBLOASUSO-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N1CCNC(=O)C1