1-Benzyl-isonipecotic acid

CAS: 10315-07-8

Ref. 3D-FB15438

Product Information

• Name: 1-Benzyl-isonipecotic acid
• Synonyms: 1-Benzylpiperidine-4-carboxylic acid, 1-(Phenylmethyl)-4-piperidinecarboxylic acid, 1-Benzyl-4-piperidine Carboxylic acid, 1-Benzyl-4-piperidinecarboxylic acid, 1-Benzyl-Isonipecotic acid, 4-Piperidinecarboxylic acid, 1-(phenylmethyl)-, Buttpark 33\04-90, Isonipecotic acid, 1-benzyl-, N-Benzyl-Isonipecotic acid, N-Benzylpiperidine-4-carboxylic acid

Description

1-Benzyl-isonipecotic acid is a chemotactic agent that has been shown to stimulate the migration of cells in cell-free systems and in blood. It activates dopamine receptors and has been shown to have neurotoxic effects at high concentrations. 1-Benzyl-isonipecotic acid also binds to the oxadiazole pharmacophore, which is a common structural motif found in many biologically active compounds. The optimization of this molecule was achieved by linking two molecules together with a linker, which resulted in an agonistic activity against the MCP1 receptor. The homology model was created using a published crystal structure and this model was used for screening purposes. This molecule showed agonistic activity against dopamine receptors, which could be useful for treating Parkinson's disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 223.27 g/mol
• Formula: C₁₂H₁₇NO₃
• Purity: Min. 95%