2N-Boc-1,2,3,4-tetrahydroisoquinolene-3S-carboxylic acid

CAS: 79261-58-8

Ref. 3D-FB15665

Product Information

• Name: 2N-Boc-1,2,3,4-tetrahydroisoquinolene-3S-carboxylic acid
• Synonyms: 2,3(1H)-isoquinolinedicarboxylic acid, 3,4-dihydro-, 2-(phenylmethyl) ester, (3S)-, (3S)-2-[(benzyloxy)carbonyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylate, (3S)-2-Carbobenzoxy-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid, Z-Tic-OH

Description

2N-Boc-1,2,3,4-tetrahydroisoquinolene-3S-carboxylic acid is a δ opioid receptor agonist. It has been shown to produce analgesia in the rat tail flick test and to inhibit electrically induced contractions of the rat ileum. This drug also binds to δ receptors with high affinity and selectivity, which may explain its potent analgesic effects. The pharmacophore model for 2N-Boc-1,2,3,4-tetrahydroisoquinolene-3S-carboxylic acid is based on the interaction of two methyl groups with the δ receptor.

• Brand: Biosynth

Chemical properties

• Molecular weight: 311.33 g/mol
• Formula: C₁₈H₁₇NO₄
• Purity: Min. 95%
• InChI: InChI=1S/C18H17NO4/c20-17(21)16-10-14-8-4-5-9-15(14)11-19(16)18(22)23-12-13-6-2-1-3-7-13/h1-9,16H,10-12H2,(H,20,21)/t16-/m0/s1
• InChI key: InChIKey=YWVQGUBCAUFBCP-INIZCTEOSA-N
• SMILES: O=C(O)[C@@H]1Cc2ccccc2CN1C(=O)OCc1ccccc1