4-benzyl-5-(2-thienyl)-1,2,4-triazole-3-thiol
CAS: 139614-67-8
Ref. 3D-FB169684
| 1g | 272.00 € | ||
| 2g | 457.00 € | ||
| 5g | 797.00 € | ||
| 250mg | 135.00 € | ||
| 500mg | 183.00 € |
Product Information
4-Benzyl-5-(2-thienyl)-1,2,4-triazole-3-thiol (BTT) is a molecule that belongs to the class of thiourea derivatives. It has been used as an anti-inflammatory agent in animal models and has shown promising results for the treatment of human inflammatory diseases. BTT is a thiol which can reversibly bind to proteins by forming a covalent bond with the sulfur atom. This interaction inhibits the production of proinflammatory cytokines such as IL-6 and TNFα by inhibiting NFκB activation. The functional theory for BTT is based on its ability to prevent the formation of reactive oxygen species by inhibiting lipid peroxidation induced by ROS. In addition, BTT may suppress inflammation through inhibition of histamine release from mast cells.
Chemical properties
Technical inquiry about: 3D-FB169684 4-benzyl-5-(2-thienyl)-1,2,4-triazole-3-thiol
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