Product Information
- (1H-Benzimidazol-2-yl)guanidine
- (E)-N-(1H-benzimidazol-2-yl)(imino)methanediaminium dichloride
- 1-(1H-1,3-Benzimidazol-2-yl)guanidine
- 1-(1H-1,3-Benzodiazol-2-yl)guanidine
- 1-(1H-Benzimidazol-2-yl)guanidine
- 1-(1H-Benzo[d]imidazol-2-yl)guanidine
- 1-(Benzimidazol-2-Yl)Guanidine
- 2-(1H-benzimidazol-2-yl)guanidine
- 2-Benzimidazolylguanidine
- Guanidine, (2-benzimidazolyl)-
- See more synonyms
- Guanidine, 1H-benzimidazol-2-yl-
- Guanidine, N-1H-benzimidazol-2-yl-
- N-(diaminomethylidene)-1H-benzimidazol-2-aminium
- NSC 10548
The protonated form of N-1H-benzimidazolylguanidine is a picolinic acid derivative that inhibits the enzyme, xanthine oxidase. The protonated form of the compound, which has a nitrogen atom in the 1 position, binds to an iron ligand in the active site of xanthine oxidase and blocks access to substrate. This inhibition prevents production of uric acid, which is responsible for gout. N-1H-Benzimidazolylguanidine is a chelate ligand that can be used as a molecular tool to identify sites on proteins where metal ions are located. It has been shown that the compound forms hydrogen bonds with other molecules such as water, xanthine, and NADH. The reaction mechanism for this compound is thought to involve intramolecular hydrogen bonding interactions and hydrogen bonding interactions with other molecules such as water or NADH.
Chemical properties
Technical inquiry about: 3D-FB175829 N-1H-Benzimidazol-2-ylguanidine
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