3-Benzoylpropanoic acid

CAS: 2051-95-8

Ref. 3D-FB18255

Product Information

• Name: 3-Benzoylpropanoic acid
• Synonyms: 4-Oxo-4-phenyl-butanoic acid4-Oxo-4-phenyl-butyric acid4-Phenyl-4-oxobutanoic acid, 2-(3-Carboxyphenyl) Propionic Acid, 3-Phenoxypropanoic Acid, 4-Oxo-4-Phenylbutanoate, 4-Oxo-4-Phenylbutanoic Acid, 4-Oxo-4-phenylbutyric acid, 4-Phenyl-4-oxobutanoic acid, Benzenebutanoic acid, γ-oxo-, Gamma-Oxo-Benzenebutanoic Acid, NSC 2092, NSC 229040, NSC 51010, Propanoic acid, 3-benzoyl-, Propionic acid, 3-benzoyl-, β-Benzoylpropionic acid, γ-Oxobenzenebutanoic acid
• CAS: 2051-95-8

Description

3-Benzoylpropanoic acid is an inhibitor of the enzyme phosphatase. It binds to the hydroxyl group of serine residues on the enzyme and prevents it from catalyzing reactions. This inhibition can lead to mitochondrial dysfunction, which may be involved in the development of autoimmune diseases such as lupus erythematosus and rheumatoid arthritis. 3-Benzoylpropanoic acid has been used successfully to treat choroidal neovascularization, a condition that causes vision loss due to abnormal blood vessel growth in the eye. The optimum pH for this drug is 7.5 and it can be broken down by a phosphatase enzyme into 2-benzoylbenzoic acid, a metabolite that is less active than 3-benzoylpropanoic acid.

• Brand: Biosynth

Chemical properties

• Molecular weight: 178.18 g/mol
• Formula: C₁₀H₁₀O₃
• Purity: Min. 95%
• InChI: InChI=1S/C10H10O3/c11-9(6-7-10(12)13)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,12,13)
• InChI key: InChIKey=KMQLIDDEQAJAGJ-UHFFFAOYSA-N
• SMILES: O=C(O)CCC(=O)c1ccccc1