Product Information
- 3-(Phenylmethyl)-3,8-diazabicyclo[3.2.1]octane
- N-Benzylnortropinone
- 8-(Phenylmethyl)-8-azabicyclo[3.2.1]octan-3-one
- 8-Aza-8-Benzylbicyclo[3,2,1]Octan-3-One
- 8-Benzylnortropan-3-One
- 8-Benzyl-8-Azabicyclo[3.2.1]Octan-3-One
- 8-Aza-8-benzylbicyclo[3,2,1]octan-3-one,8-Benzylnortropan-3-one
- 3-Benzyl-3,8-Diazabicyclo[3.2.1]Octane
- 3-Benzyl-3-Azedicyclo(3,2,1)Octan-8-One
- N-benzyl-Nortropinone
- See more synonyms
3-Benzyl-3,8-diazabicyclo[3.2.1]octane is a bicyclic compound that contains two benzene rings and an 8-carbon diazabicyclo[3.2.1]octane ring. It is a potent analgesic with affinity for opioid receptors of the μ type, which are found in the central nervous system and peripheral tissues, such as the gastrointestinal tract. 3-Benzyl-3,8-diazabicyclo[3.2.1]octane has been shown to be a μ agonist by binding to μ opioid receptors and inducing conformational changes in these proteins by occupying their binding sites on the cell surface. These conformational changes induce G protein activation and downstream signaling events that lead to inhibition of adenylate cyclase activity and opening of potassium channels, resulting in hyperpolarization of neurons and decreased neurotransmitter release from nerve terminals.
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Chemical properties
Technical inquiry about: 3D-FB18337 3-Benzyl-3,8-diazabicyclo[3.2.1]octane
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