1-Benzyl-4-benzyloxycarbonylaminopiperidine

CAS: 182223-53-6

Ref. 3D-FB18357

Product Information

• Name: 1-Benzyl-4-benzyloxycarbonylaminopiperidine
• Synonyms: [1-(Phenylmethyl)-4-piperidinyl]carbamic acid phenylmethyl ester[1-(Benzyl)-4-piperidinyl]carbamic acid benzyl esterBenzyl (1-benz ylpiperidin-4-yl)carbamate
• CAS: 182223-53-6

Description

1-Benzyl-4-benzyloxycarbonylaminopiperidine is a p38 kinase inhibitor that has been shown to have a protective effect against environmental stressors. It was shown that 1-Benzyl-4-benzyloxycarbonylaminopiperidine reduces the activity of the p38 kinase pathway and inhibits apoptosis. This agent also has an inhibitory effect on the production of proinflammatory cytokines, such as TNFα and IL-6, which are involved in the inflammatory response. The drug is currently being investigated for its potential use as an anti-cancer agent for squamous cell carcinoma.
1BZ4BCP has been shown to be well tolerated at doses up to 100mg/kg and stable in rats over 6 months, with no observable toxicity or changes in body weight, liver function, kidney function or bone marrow parameters.

• Brand: Biosynth

Chemical properties

• Molecular weight: 324.42 g/mol
• Formula: C₂₀H₂₄N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C20H24N2O2/c23-20(24-16-18-9-5-2-6-10-18)21-19-11-13-22(14-12-19)15-17-7-3-1-4-8-17/h1-10,19H,11-16H2,(H,21,23)
• InChI key: InChIKey=VZHJWMOVSNSVSX-UHFFFAOYSA-N
• SMILES: O=C(NC1CCN(Cc2ccccc2)CC1)OCc1ccccc1