R-3-(N-Benzyloxycarbonylpyrrolidin-2-ylcarbonyl)-5-bromo-1H-indole

CAS: 143322-56-9

Ref. 3D-FB18508

Product Information

• Name: R-3-(N-Benzyloxycarbonylpyrrolidin-2-ylcarbonyl)-5-bromo-1H-indole
• Synonyms: (2R)-2-[(5-Bromo-1H-indol-3-yl)carbonyl]-1-pyrrolidinecarboxylic acid phenylmethyl ester, (R)-(5-Bromo-1H-indol-3-yl)[N-[(phenylmethoxy)carbonyl]-2-pyrrolidinyl]methanone, (R)-2-[(5-Bromo-1H-indol-3-yl)carbonyl]-1-pyrrolidinecarboxylic acid benzyl ester, (R)-3-(N-Benzyloxycarbonylpyrrolidin-2-ylcarbonyl)-5-bromo-1H-indole, (R)-5-bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indole, 1-Pyrrolidinecarboxylic acid, 2-[(5-bromo-1H-indol-3-yl)carbonyl]-, phenylmethyl ester, (R)-, 1-pyrrolidinecarboxylic acid, 2-[(5-bromo-1H-indol-3-yl)carbonyl]-, phenylmethyl ester, (2R)-, Benzyl (2R)-2-[(5-bromo-1H-indol-3-yl)carbonyl]pyrrolidine-1-carboxylate, Benzyl(R)-2-(5-bromo-1H-indole-3-carbonyl)pyrrolidine-1-carboxylate, Phenylmethyl (2R)-2-[(5-bromo-1H-indol-3-yl)carbonyl]-1-pyrrolidinecarboxylate

Description

R-3-(N-Benzyloxycarbonylpyrrolidin-2-ylcarbonyl)-5-bromo-1H-indole is an inhibitor of reductase. It has been shown to inhibit liver toxicity in rats and has been studied for its potential to treat hepatic encephalopathy. R-3-(N-Benzyloxycarbonylpyrrolidin-2-ylcarbonyl)-5-bromo-1H-indole binds to the active site of reductase and inhibits the synthesis of pyrrole, which is a precursor to many chemicals in the body. In addition, it has been shown to be more potent than other reductase inhibitors in inhibiting liver toxicity in rats.

• Brand: Biosynth

Chemical properties

• Molecular weight: 427.29 g/mol
• Formula: C₂₁H₁₉BrN₂O₃
• Purity: Min. 95%
• InChI: InChI=1S/C21H19BrN2O3/c22-15-8-9-18-16(11-15)17(12-23-18)20(25)19-7-4-10-24(19)21(26)27-13-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,19,23H,4,7,10,13H2/t19-/m1/s1
• InChI key: InChIKey=CWHKVBJSRGJFFN-LJQANCHMSA-N
• SMILES: O=C(c1c[nH]c2ccc(Br)cc12)[C@H]1CCCN1C(=O)OCc1ccccc1