N-Benzyl-p-toluenesulfonamide

CAS: 1576-37-0

Ref. 3D-FB18542

Product Information

• Name: N-Benzyl-p-toluenesulfonamide
• Synonyms: 4-Methyl-N-(phenylmethyl)benzenesulfonamideBenzyl(4-toluenesulfonyl)amineN-Benzyl-p-tosylamide, 4-Methyl-N-(Phenylmethyl)-Benzenesulfonamid, 4-Methyl-N-(Phenylmethyl)Benzenesulfonamide, Benzenesulfonamide, 4-methyl-N-(phenylmethyl)-, Benzyl(4-toluenesulfonyl)amine, Labotest-Bb Lt00786416, N-Benzyl-4-Methyl-Benzenesulfonamide, N-Benzyl-4-methylbenzenesulfonamide, N-Benzyl-P-Toluenesulfonamid, N-Benzyl-P-Toluenesulfonamide, N-Benzyl-P-Toluenesulphonamide, N-Benzyl-p-tosylamide, N-Tosylbenzylamine, NSC 37123, p-Toluenesulfonamide, N-benzyl-
• CAS: 1576-37-0

Description

N-Benzyl-p-toluenesulfonamide is a calcium antagonist that reversibly binds to calcium ions. It is also known as benzothiazide and is an inotrope and a light exposure regulator. This agent has been shown to have beneficial effects on the cardiac system, such as decreasing myocardial hypertrophy and increasing contractility. N-Benzyl-p-toluenesulfonamide blocks the cardiac L type Ca2+ channel, which leads to an increase in cytosolic Ca2+. The binding of this drug to the regulatory domain of the L type Ca2+ channel has been shown using reconstituted membranes. This drug also inhibits the activity of regulatory filament proteins by binding to their N terminal regulatory domains.

• Brand: Biosynth

Chemical properties

• Molecular weight: 261.34 g/mol
• Formula: C₁₄H₁₅NO₂S
• Purity: Min. 95%
• InChI: InChI=1S/C14H15NO2S/c1-12-7-9-14(10-8-12)18(16,17)15-11-13-5-3-2-4-6-13/h2-10,15H,11H2,1H3
• InChI key: InChIKey=WTHKAJZQYNKTCJ-UHFFFAOYSA-N
• SMILES: Cc1ccc(S(=O)(=O)NCc2ccccc2)cc1