N-(2-Boc-amino)ethyl maleimide
CAS: 134272-63-2
Ref. 3D-FB18914
| 1g | To inquire | ||
| 2g | To inquire | ||
| 5g | To inquire | ||
| 250mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Wednesday 8 Jan 2025
Product Information
Name:
N-(2-Boc-amino)ethyl maleimide
Synonyms:
- N-[2-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]carbamic acid 1,1-dimethylethyl ester
- tert-butyl [2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl]carbamate
Description:
N-(2-Boc-amino)ethyl maleimide is a prodrug that hydrolyzes to form the active N-terminal amine, which can react with esterases in cells to form an intermediate reactive species. This reacts with DNA and RNA to inhibit cell growth and induce apoptosis. N-(2-Boc-amino)ethyl maleimide has been shown to have antitumor activity against HL-60 cells, which are derived from a human promyelocytic leukemia cell line.
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
240.26 g/mol
Formula:
C11H16N2O4
Purity:
Min. 95%
Color/Form:
Off-White Powder
InChI:
InChI=1S/C11H16N2O4/c1-11(2,3)17-10(16)12-6-7-13-8(14)4-5-9(13)15/h4-5H,6-7H2,1-3H3,(H,12,16)
InChI key:
InChIKey=SNYRFQCLCLMCCG-UHFFFAOYSA-N
SMILES:
CC(C)(C)OC(=O)NCCN1C(=O)C=CC1=O
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: 3D-FB18914 N-(2-Boc-amino)ethyl maleimide
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