6-Bromo nicotinic acid ethyl ester

CAS: 132334-98-6

Ref. 3D-FB19030

Product Information

• Name: 6-Bromo nicotinic acid ethyl ester
• Synonyms: 6-Bromo-3-pyridinecarboxylic acid ethyl esterEthyl 2-bromo-5-pyridinecarboxylate, Ethyl 2-bromo-5-pyridinecarboxylate, Ethyl 6-Bromopyridine-3-Carboxylate, 6-Bromonicotinicacidethylester, 6-Bromopyridine-3-carboxylic acid ethyl ester, 6-Bromonicotinic acid ethyl ester, Ethyl 2-bromopyridine-5-carboxylate
• CAS: 132334-98-6

Description

6-Bromo nicotinic acid ethyl ester is a cytotoxic agent that inhibits the growth of cancer cells. It is synthesized by dehydrating 6-bromonicotinic acid and reacting it with ethyl bromide. 6-Bromo nicotinic acid ethyl ester has been shown to have high cytotoxicity against both caco-2 and hepg2 cells, as well as inhibiting the viability of cultured human amnion epithelial cells (A431). This drug is also effective in vitro anticancer activity against human colon adenocarcinoma SW480. 6-Bromo nicotinic acid ethyl ester can be used for the detection of chloride ions in aqueous solutions using chemiluminescence. It also has anti-cancer properties, which may be due to its ability to cross-couple with DNA or its ability to induce DNA damage, leading to cell death by apoptosis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 230.06 g/mol
• Formula: C₈H₈BrNO₂
• Purity: Min. 95%
• InChI: InChI=1S/C8H8BrNO2/c1-2-12-8(11)6-3-4-7(9)10-5-6/h3-5H,2H2,1H3
• InChI key: InChIKey=NTOOSJSHTQNLKP-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1ccc(Br)nc1