6-Bromoacetyl-2-dimethylaminonaphthalene

CAS: 210832-86-3

Ref. 3D-FB19193

Product Information

• Name: 6-Bromoacetyl-2-dimethylaminonaphthalene
• Synonyms: 2-Bromo-1-[6-(dimethylamino)-2-naphthalenyl]ethanoneBADAN, 2-Bromo-1-[6-(dimethylamino)-2-naphthalenyl]ethanone, 2-Bromo-1-[6-(dimethylamino)-2-naphthyl]ethanone, 6-Bromoacetyl-2-Dimethylaminonaphthalene, Badan, Ethanone, 2-Bromo-1-[6-(Dimethylamino)-2-Naphthalenyl]-

Description

6-Bromoacetyl-2-dimethylaminonaphthalene is a cytotoxic drug that induces apoptosis by binding to the ryanodine receptor. This compound has been shown to have a high affinity for the human liver, and can induce apoptosis in human serum, magnesium salt, and soybean lipoxygenase. 6-Bromoacetyl-2-dimethylaminonaphthalene is also able to increase cytosolic calcium levels in human cells. The analytical method for 6-Bromoacetyl-2-dimethylaminonaphthalene is based on the use of annexin V, which binds to phosphatidylserine residues exposed during apoptosis. It is used as a diagnostic agent for cancerous lesions, and as a biomimetic in biochemical studies.

• Brand: Biosynth

Chemical properties

• Molecular weight: 292.17 g/mol
• Formula: C₁₄H₁₄BrNO
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C14H14BrNO/c1-16(2)13-6-5-10-7-12(14(17)9-15)4-3-11(10)8-13/h3-8H,9H2,1-2H3
• InChI key: InChIKey=ZEIHZWQYRTVVMA-UHFFFAOYSA-N
• SMILES: CN(C)c1ccc2cc(C(=O)CBr)ccc2c1