3-Butynyl tosylate

CAS: 23418-85-1

Ref. 3D-FB19592

Product Information

• Name: 3-Butynyl tosylate
• Synonyms: 3-Butyn-1-ol 1-(4-methylbenzenesulfonate)3-Butyn-1-ol p-toluenesulfonate3-Butyn-1-ol tosylate, 3-Butyn-1-ol tosylate, 3-Butyn-1-ol, 1-(4-methylbenzenesulfonate), 3-Butyn-1-ol, 4-methylbenzenesulfonate, 3-Butyn-1-ol, p-toluenesulfonate, 3-Butyn-1-yl 4-methylbenzenesulfonate, 3-Butyn-1-yl p-toluenesulfonate, 3-Butyn-1-yl p-tosylate, 3-Butyn-1-yl tosylate, 3-Butynyl 4-Methylbenzenesulfonate, 3-Butynyl 4-toluenesulfonate, 3-Butynyl p-toluenesulphonate, 4-(Tosyloxy)-1-butyne, 4-Methylbenzenesulfonic acid 3-butynyl ester, 4-p-Tolylsulfonyloxy-1-butyne, But-3-Yn-1-Yl 4-Methylbenzenesulfonate, Homopropargyl tosylate, NSC 116062, Toluene-4-sulfonic acid but-3-ynyl ester
• CAS: 23418-85-1

Description

3-Butynyl tosylate is a thiamine pyrophosphate analog that has been shown to have neuroprotective effects in experimental models of Parkinson's disease and Alzheimer's disease. 3-Butynyl tosylate prevents the formation of reactive oxygen species and has been shown to be protective against neuronal cell death in laboratory studies. 3-Butynyl tosylate is activated by the enzyme sodium carbonate and has high affinity for iron, which are both necessary for its function. It also binds to the granule neurons of the cerebellum, preventing damage from free radicals. 3-Butynyl tosylate is used clinically as an alternative treatment for cancer, especially when combined with other drugs such as uridine or halides.

• Brand: Biosynth

Chemical properties

• Molecular weight: 224.28 g/mol
• Formula: C₁₁H₁₂O₃S
• Purity: Min. 95%
• InChI: InChI=1S/CH4/h1H4
• InChI key: InChIKey=VNWKTOKETHGBQD-UHFFFAOYSA-N
• SMILES: C#CCCOS(=O)(=O)c1ccc(C)cc1