2-Bromo-3-pyridinol
CAS: 6602-32-0
Ref. 3D-FB34400
| 1kg | 1,062.00 € | ||
| 50g | 127.00 € | ||
| 100g | 191.00 € | ||
| 250g | 410.00 € | ||
| 500g | 660.00 € |
Product Information
- 2-Bromo-3-hydroxypyridine
- 2-Bromopyridin-3-Ol
- 3-Pyridinol, 2-bromo-
- Skf 75250
2-Bromo-3-pyridinol is a nicotinic acetylcholine receptor antagonist that has anti-influenza activity. It was synthesized as an analogue of the natural product pyridostigmine, which inhibited influenza in mice. 2-Bromo-3-pyridinol binds to the nicotinic acetylcholine receptor at the same site as nicotine and prevents it from being activated by acetylcholine. This drug also inhibits tumor growth and proliferation in vitro and in vivo, showing potent cytotoxicity against carcinoma cells by inhibiting protein synthesis and cell division. 2-Bromo-3-pyridinol has been shown to inhibit Alzheimer's disease in a mouse model of this disorder. The drug inhibits amyloid plaque formation and toxicity in cultured cells, suggesting its potential for treating this disease.
Chemical properties
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