1,2-Benzisoxazol-3-ylacetic acid

CAS: 4865-84-3

Ref. 3D-FB38477

Product Information

• Name: 1,2-Benzisoxazol-3-ylacetic acid
• Synonyms: 3-(Carboxylmethyl)-1,2-benzisoxazole, (1,2-Benzoxazol-3-yl)acetic acid, (Benzo[d]isoxazol-3-yl)acetic acid, 1,2-Benzisoxazol-3-Ylacetate, 1,2-Benzisoxazol-3-Ylacetic Acid, 1,2-Benzisoxazole-3-Acetic Acid, 1,2-Benzoxazol-3-Ylacetic Acid, 2-(1,2-Benzoxazol-3-yl)acetic acid, 2-(Benzisoxazol-3-yl)acetic acid, 2-(Benzo[D]Isoxazol-3-Yl)Acetic Acid, Benzisoxazol-3-ylacetic acid, NSC 179803, Salor-Int L157759-1Ea

Description

1,2-Benzisoxazol-3-ylacetic acid (BIA) is a selective agonist for the EP4 receptor. It has been shown to inhibit the proliferation of vascular smooth muscle cells and to decrease microvessel density, which is associated with decreased neuronal function. BIA also binds to the EP4 receptor in microglia, leading to an increase in energy metabolism and transcription-polymerase chain reaction (PCR). This drug has been studied as a treatment for diabetic patients and has shown promising results in clinical studies.

• Brand: Biosynth

Chemical properties

• Molecular weight: 177.16 g/mol
• Formula: C₉H₇NO₃
• Purity: Min. 95%
• InChI: InChI=1S/C9H7NO3/c11-9(12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H,11,12)
• InChI key: InChIKey=BVSIAYQIMUUCRW-UHFFFAOYSA-N
• SMILES: O=C(O)Cc1noc2ccccc12