1-Benzylpyrazole-4-boronic acid pinacol ester

CAS: 761446-45-1

Ref. 3D-FB41626

Product Information

• Name: 1-Benzylpyrazole-4-boronic acid pinacol ester
• Synonyms: 1-(Phenylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 1-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 1H-Pyrazole, 1-(phenylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
• CAS: 761446-45-1

Description

1-Benzylpyrazole-4-boronic acid pinacol ester is an additive in supercritical fluid chromatography. It has been shown to have enantioselectivity and achiral properties. The epimerization of 1-benzylpyrazole-4-boronic acid pinacol ester was found to be very sensitive to the elution conditions, with the addition of methanol as an eluent providing excellent separation. The chiral nature of 1-benzylpyrazole-4-boronic acid pinacol ester is also demonstrated by its ability to form benzodiazepine derivatives.

• Brand: Biosynth

Chemical properties

• Molecular weight: 284.16 g/mol
• Formula: C₁₆H₂₁BN₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C16H21BN2O2/c1-15(2)16(3,4)21-17(20-15)14-10-18-19(12-14)11-13-8-6-5-7-9-13/h5-10,12H,11H2,1-4H3
• InChI key: InChIKey=ZVPORPUUZXIPEF-UHFFFAOYSA-N
• SMILES: CC1(C)OB(c2cnn(Cc3ccccc3)c2)OC1(C)C