6-Bromo-4-hyrdroxyquinoline

CAS: 145369-94-4

Ref. 3D-FB41722

Product Information

• Name: 6-Bromo-4-hyrdroxyquinoline
• Synonyms: 6-Bromo-4(1H)-quinolone, 6-bromoquinolin-4(1H)-one, 4,7-Dichloro-8-Methylquinoline, 6-Bromo-Quinolin-4-Ol, 6-Bromo-4-Hyrdroxyquinoline

Description

6-Bromo-4-hydroxyquinoline is a synthetic compound that has been shown to inhibit the growth of cancer cells. The synthesis of 6-bromo-4-hydroxyquinoline is achieved by reacting 4,5,6,7-tetrabromoquinoline with hydroxylamine in the presence of a base. This process forms 6-bromo-4-hydroxyquinoline in high yield and purity. A number of studies have shown that 6-bromo-4-hydroxyquinoline inhibits tumor cell proliferation and induces apoptosis in vitro. It also exhibits antiangiogenic activity by inhibiting the PI3K/mTOR pathway and angiogenesis through the inhibition of VEGF production.
6 - bromo - 4 - hydroxy quinoline can be used as an effective chemotherapeutic agent for cancers such as breast cancer, melanoma, lung cancer, prostate cancer, and

• Brand: Biosynth

Chemical properties

• Molecular weight: 224.05 g/mol
• Formula: C₉H₆BrNO
• Purity: Min. 95%
• InChI: InChI=1S/C9H6BrNO/c10-6-1-2-8-7(5-6)9(12)3-4-11-8/h1-5H,(H,11,12)
• InChI key: InChIKey=XKLBNOHKHRAXKK-UHFFFAOYSA-N
• SMILES: O=c1cc[nH]c2ccc(Br)cc12