2,2'-Biquinoline-4,4'-dicarboxylic acid

CAS: 1245-13-2

Ref. 3D-FB45060

Product Information

• Name: 2,2'-Biquinoline-4,4'-dicarboxylic acid
• Synonyms: 2,2'-Bicinchoninic acid, (2,2′)Biquinolinyl-4,4′-dicarboxylic acid, 2,2'-Bicinchoninic Acid, 2,2′-Dicinchoninic acid, 2-(4-Carboxyquinolin-2-yl)quinoline-4-carboxylic acid, 4,4′-Dicarboxy-2,2′-biquinoline, Bicinchoninic acid, NSC 133815
• CAS: 1245-13-2

Description

2,2'-Biquinoline-4,4'-dicarboxylic acid is a naturally occurring molecule that has been shown to have potent antimicrobial activity against Gram-positive and Gram-negative bacteria. It interacts with the protein in the cell membrane and blocks iron uptake by the bacteria, which causes oxidative stress and leads to cell death. The compound also inhibits DNA synthesis by binding to the enzyme polymerase chain reaction (PCR). This binding prevents DNA replication and transcription. 2,2'-Biquinoline-4,4'-dicarboxylic acid has been shown to have antiviral properties in vitro. It also binds to human serum proteins through a covalent bond and can be detected using fluorescence probe methods or plasma mass spectrometry.

• Brand: Biosynth

Chemical properties

• Molecular weight: 344.32 g/mol
• Formula: C₂₀H₁₂N₂O₄
• Purity: Min. 95%
• InChI: InChI=1S/C20H12N2O4/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18/h1-10H,(H,23,24)(H,25,26)
• InChI key: InChIKey=AFYNADDZULBEJA-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(-c2cc(C(=O)O)c3ccccc3n2)nc2ccccc12