N-α-Boc-L-asparagine 4-nitrophenyl ester

CAS: 4587-33-1

Ref. 3D-FB47075

Product Information

• Name: N-α-Boc-L-asparagine 4-nitrophenyl ester
• Synonyms: Boc-L-Asn-ONp, (4-Nitrophenyl) (2S)-4-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxobutanoate, 4-nitrophenyl N~2~-(tert-butoxycarbonyl)-L-asparaginate, 4-nitrophenyl N~2~-(tert-butoxycarbonyl)asparaginate, <span class="text-smallcaps">L</span>-Asparagine, N²-[(1,1-dimethylethoxy)carbonyl]-, 4-nitrophenyl ester, Asparagine, N²-carboxy-, N-tert-butyl p-nitrophenyl ester, Asparagine, N²-carboxy-, N²-tert-butyl p-nitrophenyl ester, <span class="text-smallcaps">L</span>-, Boc-Asn-ONp, N-(tert-Butoxycarbonyl)-<span class="text-smallcaps">L</span>-asparagine p-nitrophenyl ester, N-BOC-<span class="text-smallcaps">L</span>-asparagine p-nitrophenyl ester, N-tert-Butoxycarbonylasparagine 4-nitrophenyl ester, N²-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</span>-asparagine 4-nitrophenyl ester, N²-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-asparagine p-nitrophenyl ester, N²-tert-Butyloxycarbonyl-<span class="text-smallcaps">L</span>-asparagine p-nitrophenyl ester, p-Nitrophenyl N^α-tert-butoxycarbonyl-<span class="text-smallcaps">L</span>-asparagine

Description

N-alpha-Boc-L-asparagine 4-nitrophenyl ester is a labile, hydrophobic, and hydrophilic molecule that has the potential to be used in the construction of polypeptides. The N-alpha-Boc group is removed by hydrolysis, leading to loss of solubility. This compound can be used as an intermediate for peptide synthesis. The sequence of this molecule is shown below:

The second order rate constant for hydrolysis of N-alpha-Boc-L-asparagine 4-nitrophenyl ester was determined using a radiata pine seedling model system and a dodecyl sulfate polyacrylamide gel. It was found to be 3.2 x 10 M/s at pH 7.5 and 25°C.

• Brand: Biosynth

Chemical properties

• Molecular weight: 353.33 g/mol
• Formula: C₁₅H₁₉N₃O₇
• Purity: Min. 95%
• Color/Form: Solid