Boc-L-isoleucine N-hydroxysuccinimide ester

CAS: 3392-08-3

Ref. 3D-FB47752

Product Information

• Name: Boc-L-isoleucine N-hydroxysuccinimide ester
• Synonyms: Boc-L-Ile-OSu, 2,5-Pyrrolidinedione, 1-[[N-[(1,1-dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</span>-isoleucyl]oxy]-, 2,5-dioxopyrrolidin-1-yl N-(tert-butoxycarbonyl)-L-isoleucinate, 2,5-dioxopyrrolidin-1-yl N-(tert-butoxycarbonyl)isoleucinate, 33: PN: US20070066537 PAGE: 12 claimed protein, <span class="text-smallcaps">L</span>-Isoleucine, 2,5-pyrrolidinedione deriv., <span class="text-smallcaps">L</span>-Isoleucine, N-[(1,1-dimethylethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester, Boc-Ile-OSu, Carbamic acid, [(1S,2S)-1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-methylbutyl]-, 1,1-dimethylethyl ester, Carbamic acid, [1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-methylbutyl]-, 1,1-dimethylethyl ester, [S-(R*,R*)]-, N-(tert-Butoxycarbonyl)-<span class="text-smallcaps">L</span>-isoleucine succinimide ester, N-(tert-Butyloxycarbonyl)-<span class="text-smallcaps">L</span>-isoleucine N-hydroxysuccinimide ester, NSC 334339, Succinimide, N-[(N-carboxy-<span class="text-smallcaps">L</span>-isoleucyl)oxy]-, tert-butyl ester

Description

Boc-L-isoleucine N-hydroxysuccinimide ester is an inhibitor of the bacterial biosynthetic pathway. It blocks the synthesis of the amino acid L-isoleucine by binding to the enzyme IleS synthetase, which catalyzes the conversion of L-threonine to L-isoleucine in bacteria. The compound is a benzodiazepine receptor ligand that has been shown to inhibit bacterial growth in vitro and in vivo. Boc-L-isoleucine N-hydroxysuccinimide ester binds to the outer membrane of Gram negative bacteria and causes leakage from the cytoplasmic membrane, leading to cell death. This compound also inhibits methicillin resistant Staphylococcus aureus (MRSA) from binding to human cells.br>br>
Boc-L-isoleucine N-hydroxysuccinimide ester

• Brand: Biosynth

Chemical properties

• Molecular weight: 328.36 g/mol
• Formula: C₁₅H₂₄N₂O₆
• Purity: Min. 95%