Boc-L-methionine N-hydroxysuccinimide ester

CAS: 3845-64-5

Ref. 3D-FB47812

Product Information

• Name: Boc-L-methionine N-hydroxysuccinimide ester
• Synonyms: Boc-L-Met-OSu, (2,5-Dioxopyrrolidin-1-yl) (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoate, 2,5-dioxopyrrolidin-1-yl N-(tert-butoxycarbonyl)methioninate, <span class="text-smallcaps">L</span>-Methionine, N-[(1,1-dimethylethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester, BOC-Met-NHS, Boc-Met-OSu, Carbamic acid, [(1S)-1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-3-(methylthio)propyl]-, 1,1-dimethylethyl ester, Carbamic acid, [1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-3-(methylthio)propyl]-, 1,1-dimethylethyl ester, (S)-, Methionine, N-carboxy-, N-tert-butyl ester, succinimido deriv., <span class="text-smallcaps">L</span>-, N-(tert-Butyloxycarbonyl)-<span class="text-smallcaps">L</span>-methionine ester with N-hydroxysuccinimide, NSC 343722, Succinimide, N-[(N-carboxy-<span class="text-smallcaps">L</span>-methionyl)oxy]-, tert-butyl ester
• CAS: 3845-64-5

Description

Boc-L-methionine N-hydroxysuccinimide ester is an analytical method that uses a fluorescence-based reaction to conjugate drugs to lysine residues on proteins. The Boc-L-methionine N-hydroxysuccinimide ester reacts with the hydroxysuccinimide group of lysine residues and the drug, forming a covalent link between the two. This reaction produces a fluorescent product that can be detected by mass spectrometry, which is used to identify protein targets for drug molecules. This technique has been utilized in cancer research, as well as other fields such as neuroscience.

• Brand: Biosynth

Chemical properties

• Molecular weight: 346.4 g/mol
• Formula: C₁₄H₂₂N₂O₆S
• Purity: Min. 95%
• InChI: InChI=1S/C14H22N2O6S/c1-14(2,3)21-13(20)15-9(7-8-23-4)12(19)22-16-10(17)5-6-11(16)18/h9H,5-8H2,1-4H3,(H,15,20)/t9-/m0/s1
• InChI key: InChIKey=PCZJWSPKNYONIM-VIFPVBQESA-N
• SMILES: CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)ON1C(=O)CCC1=O