N,O-Bis-acetyl-L-tyrosine

CAS: 17355-23-6

Ref. 3D-FB49533

Product Information

• Name: N,O-Bis-acetyl-L-tyrosine
• Synonyms: Ac-L-Tyr(Ac)-OH, (S)-2-Acetamido-3-(4-acetoxyphenyl)propanoic acid, <span class="text-smallcaps">L</span>-Tyrosine, N,O-diacetyl-, <span class="text-smallcaps">L</span>-Tyrosine, N-acetyl-, acetate (ester), Ac-Tyr(Ac)-OH, N,O-Diacetyl-<span class="text-smallcaps">L</span>-tyrosine, N,O-diacetyl-L-tyrosine, N-acetyl-O-acetyl-L-tyrosine, O,N-Diacetyl-<span class="text-smallcaps">L</span>-tyrosine, Tyrosine, N-acetyl-, acetate (ester), <span class="text-smallcaps">L</span>-

Description

N,O-Bis-acetyl-L-tyrosine is a bioreversible acetylated amino acid that is synthesized from L-tyrosine. It can be used in the preparation of creatine kinase. N,O-Bis-acetyl-L-tyrosine has been shown to bind to the aromatic residues on creatine kinase and inhibit its activity. The acetylation of lysine residues may be reversible, but this process requires the presence of a hydroxyl group on the tyrosine residue. This reaction is catalyzed by a lysine residue on creatine kinase. Studies have shown that the kinetic properties of N,O-Bis-acetyl-L-tyrosine are similar to those of L-tyrosine and therefore it can be used as an alternative substrate for creatine biosynthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 265.26 g/mol
• Formula: C₁₃H₁₅NO₅
• Purity: Min. 98 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C13H15NO5/c1-8(15)14-12(13(17)18)7-10-3-5-11(6-4-10)19-9(2)16/h3-6,12H,7H2,1-2H3,(H,14,15)(H,17,18)/t12-/m0/s1
• InChI key: InChIKey=ZUAVWNTVXZCOEL-LBPRGKRZSA-N
• SMILES: CC(=O)N[C@@H](Cc1ccc(OC(C)=O)cc1)C(=O)O