3-(Boc-4-aminophenyl)propionic acid

CAS: 149506-05-8

Ref. 3D-FB49901

Product Information

• Name: 3-(Boc-4-aminophenyl)propionic acid
• Synonyms: 3-(Boc-4-Aminophenyl)-Propionic Acid, 3-{4-[(Tert-Butoxycarbonyl)Amino]Phenyl}Propanoic Acid, 4-[[(1,1-Dimethylethoxy)carbonyl]amino]benzenepropanoic acid, Benzenepropanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-

Description

3-(Boc-4-aminophenyl)propionic acid is a potent inhibitor of alpha-glucosidase. The compound has been shown to inhibit the activity of both olefinic and dihydroxy substrates, acting as an olefinic substrate inhibitor in a molecular docking simulation. 3-(Boc-4-aminophenyl)propionic acid also has a sulfonamide moiety that has shown inhibitory activity against alpha-glucosidase. This inhibition may be due to the phenyl ring's ability to form hydrogen bonds with key amino acid residues on the enzyme surface. 3-(Boc-4-aminophenyl)propionic acid was found to inhibit alpha glucosidase in vitro, causing a decrease in blood glucose levels in mice.

• Brand: Biosynth

Chemical properties

• Molecular weight: 265.31 g/mol
• Formula: C₁₄H₁₉NO₄
• Purity: Min. 95%
• InChI: InChI=1S/C14H19NO4/c1-14(2,3)19-13(18)15-11-7-4-10(5-8-11)6-9-12(16)17/h4-5,7-8H,6,9H2,1-3H3,(H,15,18)(H,16,17)
• InChI key: InChIKey=ZENOSLRCCHSZKU-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)Nc1ccc(CCC(=O)O)cc1