Boc-cis-4-fluoro-L-proline

CAS: 203866-13-1

Ref. 3D-FB50547

Product Information

• Name: Boc-cis-4-fluoro-L-proline
• Synonyms: (2S,4S)-Boc-4-fluoro-pyrrolidine-2-carboxylic acid, (2S,4S)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic acid, (2S,4S)-1-(tert-Butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylicaci, (2S,4S)-1-(tert-butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid, (2S,4S)-4-Fluoro-1-tert-butoxycarbonyl-pyrrolidine-2-carboxylic acid, (4S)-1-(tert-butoxycarbonyl)-4-fluoro-L-proline, (4S)-1-tert-Butoxycarbonyl-4-fluoro-<span class="text-smallcaps">L</span>-proline, 1,2-Pyrrolidinedicarboxylic acid, 4-fluoro-, 1-(1,1-dimethylethyl) ester, (2S,4S)-, 1,2-Pyrrolidinedicarboxylic acid, 4-fluoro-, 1-(1,1-dimethylethyl) ester, (2S-cis)-, 1-(1,1-Dimethylethyl) (2S,4S)-4-fluoro-1,2-pyrrolidinedicarboxylate, Boc-cis-4-F-L-Pro-OH, Boc-cis-4-fluoro-Pro-OH, N-BOC-cis-4-fluoro-L-proline, N-t-BOC-cis-4-Fluoro-L-proline, N-tert-BOC-cis-4-fluoro-<span class="text-smallcaps">L</span>-proline

Description

Boc-cis-4-fluoro-L-proline is a fluorinated proline derivative. It has been shown to be an efficient and selective reagent for the preparation of trans-4-hydroxy-l-proline methyl esters, which are used in peptide synthesis. The yields of this transformation are high and can be achieved in one step with good functional group tolerance. This compound is also useful for the synthesis of other fluorinated compounds.

• Brand: Biosynth

Chemical properties

• Molecular weight: 233.24 g/mol
• Formula: C₁₀H₁₆FNO₄
• Purity: Min. 95%
• InChI: InChI=1S/C10H16FNO4/c1-10(2,3)16-9(15)12-5-6(11)4-7(12)8(13)14/h6-7H,4-5H2,1-3H3,(H,13,14)/t6-,7-/m0/s1
• InChI key: InChIKey=YGWZXQOYEBWUTH-BQBZGAKWSA-N
• SMILES: CC(C)(C)OC(=O)N1C[C@@H](F)C[C@H]1C(=O)O