Boc-cis-4-hydroxy-L-proline

CAS: 87691-27-8

Ref. 3D-FB50571

Product Information

• Name: Boc-cis-4-hydroxy-L-proline
• Synonyms: (2S,4S)-cis-1-N-Boc-4-hydroxy-prolineBoc-(2S,4S)-(-)-4-hydroxypyrrolidine-2-carboxylic acid, N-(tert-butoxycarbonyl)-cis-4-hydroxy-L-proline, N-Boc-cis-4-hydroxypyrrolidine-2-carboxylic acid, N-Boc-cis-4-hydroxy-L-proine, (4S)-1-(tert-butoxycarbonyl)-4-hydroxy-L-proline, BOC-cis-4-hydroxy-L-proline, N-Boc-Cis-4-Hydroxy-L-Proline, cis-boc-Hyp-OH, Boc-cis-Hyp-OH
• CAS: 87691-27-8

Description

Enduracididine is a molecule that inhibits dipeptidyl peptidase-4 (DPP-4) and is orally active. Enduracididine is synthesized from the amino acid proline by an enzymatic process, which requires a number of impurities. The synthetic process for enduracididine starts with the chemoenzymatic synthesis of L-alanyl-L-cysteine methyl ester, followed by the coupling of this compound with L-proline to yield enduracididine. Enduracididine's potent inhibition of DPP-4 has been shown in both cytosolic and plasma glucose levels in mice. The drug also decreases plasma glucose levels in diabetic rats and reduces hyperglycemia induced by streptozotocin.

• Brand: Biosynth

Chemical properties

• Molecular weight: 231.25 g/mol
• Formula: C₁₀H₁₇NO₅
• Purity: Min. 95%