5-Bromo-1H-indazole
CAS: 53857-57-1
Ref. 3D-FB50830
| 1g | Discontinued | ||
| 2g | Discontinued | ||
| 5g | Discontinued | ||
| 10g | Discontinued | ||
| 25g | Discontinued |
Product Information
Name:
5-Bromo-1H-indazole
Synonyms:
- 5-Bromoindazole
- 5-Bromoindazol
Description:
5-Bromo-1H-indazole is an indazole derivative that has been shown to have potential use in the treatment of pain. It binds to the allosteric site on the enzyme gyrase, which is a DNA topoisomerase that controls the supercoiling of DNA. This binding prevents ATP from binding and inhibits DNA unwinding, leading to a decrease in DNA synthesis and cell division. 5-Bromo-1H-indazole also binds with high affinity at the allosteric site on the enzyme adenylate cyclase, which is involved in signal transduction pathways. Binding of 5-bromo-1H-indazole causes an increase in cAMP levels and leads to functional effects such as antinociception.
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
197.03 g/mol
Formula:
C7H5BrN2
Purity:
Min. 95%
InChI:
InChI=1S/C7H5BrN2/c8-6-1-2-7-5(3-6)4-9-10-7/h1-4H,(H,9,10)
InChI key:
InChIKey=STVHMYNPQCLUNJ-UHFFFAOYSA-N
SMILES:
Brc1ccc2[nH]ncc2c1
MDL:
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HS code:
