1-N-Boc-piperidine-4-thiocarboxamide

CAS: 214834-18-1

Ref. 3D-FB53494

Product Information

• Name: 1-N-Boc-piperidine-4-thiocarboxamide
• Synonyms: tert-Butyl 4-(aminocarbothioyl)tetrahydropyridine-1(2H)-carboxylate, Tert-Butyl 4-Carbamothioylpiperidine-1-Carboxylate, N-BOC-piperidine-4-carbothioamide

Description

1-N-Boc-piperidine-4-thiocarboxamide is a template molecule that has been optimized for its potential anti-malarial activity. It is a potent and selective inhibitor of protein kinase C (PKC) and can inhibit the growth of plasmodium falciparum in culture. PKC is an enzyme that regulates intracellular signaling pathways, which are responsible for cell growth, differentiation, and survival. 1-N-Boc-piperidine-4-thiocarboxamide blocks the production of cyclic GMP (cGMP), which is required for the regulation of cellular processes such as proliferation and differentiation. This molecule has shown to have a hypoglycemic effect in animal models.

• Brand: Biosynth

Chemical properties

• Molecular weight: 244.36 g/mol
• Formula: C₁₁H₂₀N₂O₂S
• Purity: Min. 95%
• InChI: InChI=1S/C11H20N2O2S/c1-11(2,3)15-10(14)13-6-4-8(5-7-13)9(12)16/h8H,4-7H2,1-3H3,(H2,12,16)
• InChI key: InChIKey=SCGQNJHAAYUQOO-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC(C(N)=S)CC1