Bucindolol

CAS: 70369-47-0

Ref. 3D-FB53609

Product Information

• Name: Bucindolol
• Synonyms: 2-[2-Hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]benzonitrile, 2-(2-hydroxy-3-{[1-(1H-indol-3-yl)-2-methylpropan-2-yl]amino}propoxy)benzonitrile hydrochloride (1:1), <span class="text-smallcaps">DL</span>-Bucindolol hydrochloride, Benzonitrile, 2-[2-hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]-, hydrochloride (1:1), Benzonitrile, 2-[2-hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]-, monohydrochloride, Bucindolol hydrochloride, Mj-13105-1, o-[2-Hydroxy-3-[(2-indol-3-yl-1,1-dimethylethyl)amino]propoxy]benzonitrile monohydrochloride

Description

Bucindolol is a beta-blocker that has been shown to have cardiac, receptor activity, atrial, and myocardial infarct properties. It also has natriuretic peptide levels and biological sample properties. Bucindolol binds to beta-adrenergic receptors in the heart, which leads to decreased heart rate, increased systolic pressure, and relaxation of the papillary muscles. This drug has also been shown to inhibit the production of proprotein convertase subtilisin/kexin type 9 (PCSK9) in vitro.

• Brand: Biosynth

Chemical properties

• Molecular weight: 363.45 g/mol
• Formula: C₂₂H₂₅N₃O₂
• Purity: Min. 95%
• InChI: InChI=1S/C22H28N2O2/c1-16-8-4-7-11-21(16)26-15-18(25)14-24-22(2,3)12-17-13-23-20-10-6-5-9-19(17)20/h4-11,13,18,23-25H,12,14-15H2,1-3H3
• InChI key: InChIKey=LBQVRBUQVRRHIB-UHFFFAOYSA-N
• SMILES: CC(C)(Cc1c[nH]c2ccccc12)NCC(O)COc1ccccc1C#N