6-Bromo-4-hydroxycoumarin
CAS: 4139-61-1
Ref. 3D-FB53836
| 1g | To inquire | |
| 2g | To inquire | |
| 5g | To inquire | |
| 10g | To inquire | |
| 25g | To inquire |
Product Information
- 6-Bromo-4-hydroxy-2H-chromen-2-one
- 2H-1-Benzopyran-2-one, 6-bromo-4-hydroxy-
6-Bromo-4-hydroxycoumarin, also known as BrHCC, is an organic compound that belongs to the tetronic acid family. It was first synthesized in 1891 by the reaction of ethyl nitroacetate and homophthalic acid. 6-Bromo-4-hydroxycoumarin is a valued reagent for the synthesis of 1,3-dicarbonyl compounds due to its high yields, easy workup, and stereoselectivity. The synthesis of 6-bromo-4-hydroxycoumarin begins with the condensation of ethyl nitroacetate with pyridine in presence of hydrochloric acid to produce a mixture of methylene chloride and 4-hydroxycoumarin. This mixture is then heated at reflux for 24 hours. The final product is purified by fractional distillation.
Chemical properties
Technical inquiry about: 3D-FB53836 6-Bromo-4-hydroxycoumarin
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