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5-Bromopyrazine-2-carbonitrile
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5-Bromopyrazine-2-carbonitrile

CAS: 221295-04-1

Ref. 3D-FB54487

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Estimated delivery in United States, on Thursday 2 Jan 2025

Product Information

Name:
5-Bromopyrazine-2-carbonitrile
Synonyms:
  • 2-Bromo-5-cyanopyrazine
  • 2-Pyrazinecarbonitrile, 5-bromo-
  • 5-Bromo-2-pyrazinecarbonitrile
  • T6N Dnj Be Ecn
Description:

5-Bromopyrazine-2-carbonitrile is a structural analog of the amide inhibitor bace1, which is currently in preclinical development. This compound has been shown to have potent activity against Alzheimer's disease, with no significant toxicity. 5-Bromopyrazine-2-carbonitrile binds to the amyloid precursor protein and inhibits its cleavage by the enzyme BACE1, which leads to reduced production of amyloid beta peptides. In addition, this compound has been shown to inhibit the activity of BACE1 at low concentrations as well as other enzymes involved in amyloid beta production.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
183.99 g/mol
Formula:
C5H2BrN3
Purity:
Min. 95%
InChI:
InChI=1S/H3N/h1H3
InChI key:
InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
SMILES:
N#Cc1cnc(Br)cn1
MDL:
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EINECS:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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