2-Bromo-3-amine-6-methylpyridine

CAS: 126325-53-9

Ref. 3D-FB55481

Product Information

• Name: 2-Bromo-3-amine-6-methylpyridine
• Synonyms: 3-Amino-2-bromo-6-picoline, (2-Bromo-6-methylpyridin-3-yl)amine, 2-Bromo-3-Amino-6-Methylpyridine, 2-Bromo-3-Amino-6-Picoline, 2-Bromo-6-Methylpyridin-3-Amine, 2-Bromo-6-methyl-3-pyridinamine, 3-Amino-2-Bromo-6-Methylpyridin, 3-Amino-2-Bromo-6-Picoline, 3-Amino-2-Bromo-6-Pyridine, 3-Pyridinamine, 2-bromo-6-methyl-, 6-Bromo-5-amino-2-picoline

Description

2-Bromo-3-amine-6-methylpyridine is a potent inhibitor of the TGF-β receptor kinase. This compound has been shown to inhibit the growth of human breast cancer cells in vitro and in vivo. 2-Bromo-3-amine-6-methylpyridine also inhibits the production of antiangiogenic factors, such as TGF-β, which may be responsible for its antitumor activity. The potency of this drug was measured in a kinase assay that uses luciferase as a reporter.

• Brand: Biosynth

Chemical properties

• Molecular weight: 187.04 g/mol
• Formula: C₆H₇BrN₂
• Purity: Min. 95%
• InChI: InChI=1S/C6H7BrN2/c1-4-2-3-5(8)6(7)9-4/h2-3H,8H2,1H3
• InChI key: InChIKey=KLVZEEUNGGOROA-UHFFFAOYSA-N
• SMILES: Cc1ccc(N)c(Br)n1