6-bromo-4-methylquinoline

CAS: 41037-28-9

Ref. 3D-FB58969

Product Information

• Name: 6-bromo-4-methylquinoline
• Synonyms: Quinoline, 6-Bromo-4-Methyl-

Description

6-bromo-4-methylquinoline is a quinoline derivative that inhibits the growth of cancer cells. It is an inhibitor of kinases and has been shown to inhibit tumor growth in vitro and in vivo in u87mg cells. 6-Bromo-4-methylquinoline also inhibits the activation of estrogen receptors, which may contribute to its anti-cancer activity. The optimal concentration for 6-bromo-4-methylquinoline is between 10 and 30 μM, with an IC50 of about 30 μM. This drug can be used as a radiation sensitizer for ionizing radiation therapy, but it does not have any effect on chloride levels in plasma.

• Brand: Biosynth

Chemical properties

• Molecular weight: 222.08 g/mol
• Formula: C₁₀H₈NBr
• Purity: Min. 95%
• InChI: InChI=1S/C10H8BrN/c1-7-4-5-12-10-3-2-8(11)6-9(7)10/h2-6H,1H3
• InChI key: InChIKey=XBZQSJLYRMZRSZ-UHFFFAOYSA-N
• SMILES: Cc1ccnc2ccc(Br)cc12