Product Information
Name:
4-(1,3-benzothiazol-2-yl)aniline
Synonyms:
- benzenamine
- 4-(2-benzothiazolyl)-
- 2-(4-Aminophenyl)-1,3-benzothiazole
- 2-(4-Aminophenyl)Benzothiazole
- 2-(4-Aminophenyl)benzo[d]thiazole
- 2-(p-Aminophenyl)benzothiazole
- 4-(2-Benzothiazolyl)benzenamine
- 4-(Benzo[d]thiazol-2-yl)aniline
- 4-(Benzo[d]thiazol-2-yl)benzenamine
- 4-(Benzothiazol-2-yl)aniline
- See more synonyms
- 4-Benzothiazol-2-Yl-Phenylamine
- 4-Benzothiazol-2-ylphenylamine
- Benzenamine, 4-(2-benzothiazolyl)-
- Benzothiazole, 2-(p-aminophenyl)-
- Cjm 126
- NSC 34445
Description:
4-(1,3-Benzothiazol-2-yl)aniline is a potent antitumor agent that has been shown to inhibit the growth of cancer cells in vitro and in vivo. It binds to and inhibits the function of epidermal growth factor receptors (EGFRs) on the surface of cancer cells. This binding prevents the activation of EGFRs by their ligands, epidermal growth factor and amphiregulin. 4-(1,3-Benzothiazol-2-yl)aniline also inhibits cyclin D1 and CDK4, which are necessary for cell division. It is also an antimicrobial agent against bacteria and fungi, although it has no effect on mammalian cells.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
226.3 g/mol
Formula:
C13H10N2S
Purity:
Min. 95%
InChI:
InChI=1S/C13H10N2S/c14-10-7-5-9(6-8-10)13-15-11-3-1-2-4-12(11)16-13/h1-8H,14H2
InChI key:
InChIKey=WKRCOZSCENDENK-UHFFFAOYSA-N
SMILES:
Nc1ccc(-c2nc3ccccc3s2)cc1
MDL:
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HS code:
