(S)-1-(tert-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

CAS: 26839-75-8

Ref. 3D-FB61491

Product Information

• Name: (S)-1-(tert-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
• Synonyms: Timolol, (-)-S-Timolol, (-)-Timolol, (2S)-1-(tert-Butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol, (2S)-1-(tert-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol, (2S)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol, (S)-1-(terc-butilamino)-3-[(4-morfolino-1,2,5-tiadiazol-3-il)oxi]propan-2-ol, (S)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazole-3-yl)oxy]propane-2-ol, 1,2,5-Thiadiazole, 2-propanol deriv., 2-Propanol, 1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-, (S)-(-)-, 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-, (S)-, <span class="text-smallcaps">L</span>-Timolol, Arutimol, Oftensin, l-Timolol

Description

Timolol is a beta-adrenergic blocker drug that is used to treat glaucoma and other eye diseases. Timolol blocks the action of catecholamines (e.g., adrenaline) on the beta-receptors in the eye, which decreases intraocular pressure. Timolol maleate is available as an ophthalmic solution and tablet for oral use. The most common side effect of timolol is constipation; however, it has been shown to cause bowel disease in some cases. Timolol also has been shown to have mitochondrial functions, inhibiting electron transport, and can have interactions with drugs such as benzalkonium chloride. The pharmacological effects of timolols are dose-dependent and reversible if discontinued. Timolols have been used in combination therapy groups for the treatment of intraocular hypertension or chronic open angle glaucoma in patients who are not responsive to conventional therapy with beta blockers or alpha agonists alone.

• Brand: Biosynth

Chemical properties

• Molecular weight: 316.42 g/mol
• Formula: C₁₃H₂₄N₄O₃S
• Purity: Min. 95%
• InChI: InChI=1S/C13H24N4O3S/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17/h10,14,18H,4-9H2,1-3H3/t10-/m0/s1
• InChI key: InChIKey=BLJRIMJGRPQVNF-JTQLQIEISA-N
• SMILES: CC(C)(C)NC[C@H](O)COc1nsnc1N1CCOCC1