Benzo-12-crown 4-Ether

CAS: 14174-08-4

Ref. 3D-FB62069

Product Information

• Name: Benzo-12-crown 4-Ether
• Synonyms: 2,3-Benzo-1,4,7,10-tetraoxadodec-2-ene, Benzo-12-Crown 4-Ether, 2,3-Benzo-1,4,7,10-Tetraoxadodec-2-Ene, 6,7,9,10,12,13-Hexahydrobenzo[1,4,7,10]Tetraoxocyclododecin, 4,7,10-Benzotetraoxacyclododecin,2,3,5,6,8,9-hexahydro-1, Benzo-12-Crown-4 98+%, Benzo-12-crown-4, 99+%, Methyl 3-(3,4-Dimethoxyphenyl)Propanoate, 2,3,5,6,8,9-Hexahydro-1,4,7,10-Benzotetraoxacyclododecine

Description

Benzo-12-crown 4-ether is a chemical compound that belongs to the class of benzo crown ethers. It has an optimum concentration of 0.1 M and is soluble in organic solvents such as chloroform, methanol, ethanol, acetone, ethyl acetate, and tetrahydrofuran. Benzo-12-crown 4-ether has been shown to be a potent inhibitor of the tyrosine kinase activity of icotinib hydrochloride (IH) with a binding constant of 1.5 × 10 M. The molecule adopts a rigid structure due to its benzene ring and four ether groups attached to the phenyl group. The molecular weight is 576 g/mol and it has an optical rotation of +27°. FTIR spectroscopy was used to identify functional groups present in this molecule as well as its ring opening in acidic environments at pH 2.
Benzo-12-c

• Brand: Biosynth

Chemical properties

• Purity: Min. 95%