3-Bromo-5-(trifluoromethyl)benzoic acid

CAS: 328-67-6

Ref. 3D-FB64188

Product Information

• Name: 3-Bromo-5-(trifluoromethyl)benzoic acid
• Synonyms: Bromotrifluoromethylbenzoic acid, Benzoic acid, 3-bromo-5-(trifluoromethyl)-

Description

3-Bromo-5-(trifluoromethyl)benzoic acid is a drug resistant hydroxamic acid that can be used to treat tuberculosis. 3-Bromo-5-(trifluoromethyl)benzoic acid inhibits the growth of Mycobacterium tuberculosis and has been shown to be effective against multi-drug resistant strains of Mycobacterium tuberculosis. 3-Bromo-5-(trifluoromethyl)benzoic acid has also been shown to inhibit the synthesis of proteins by blocking the production of amino acids. The drug blocks protein synthesis by inhibiting an enzyme called hydroxamate methyltransferase, which is responsible for converting N5,N10-methylenetetrahydrofolate into 5,10 methylenetetrahydrofolate (an important cofactor in protein synthesis).

• Brand: Biosynth

Chemical properties

• Molecular weight: 269.02 g/mol
• Formula: C₈H₄BrF₃O₂
• Purity: Min. 95%
• InChI: InChI=1S/C8H4BrF3O2/c9-6-2-4(7(13)14)1-5(3-6)8(10,11)12/h1-3H,(H,13,14)
• InChI key: InChIKey=AMZBKZQMAZWIJM-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(Br)cc(C(F)(F)F)c1