5-Bromo-2-methoxyphenol

CAS: 37942-01-1

Ref. 3D-FB72058

Product Information

• Name: 5-Bromo-2-methoxyphenol
• Synonyms: 2-Methoxy-5-bromophenol, 3-Hrdroxy-4-Methoxy Bromobenzene, 3-Hydroxy-4-Methoxy Bromobenzene, 3-Hydroxy-4-methoxybromobenzene, 5-Bromo-2-methoxy-phenol, 5-Bromoguaiacol, Phenol, 5-bromo-2-methoxy-
• CAS: 37942-01-1

Description

Bosutinib is a tyrosine kinase inhibitor that is used to treat chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). Bosutinib inhibits the activity of the Bcr-Abl protein, which is overexpressed in CML cells. The drug has been shown to be effective in primary myelofibrosis, a disease characterized by the production of excess blood cells. Bosutinib also binds stereoselectively to primary amines. This drug inhibits the activity of protein kinase C and protein kinase A, which are enzymes involved in cellular function. Bosutinib has been shown to inhibit growth and induce apoptosis in human K562 cells at low doses, with dose-dependent effects.

• Brand: Biosynth

Chemical properties

• Molecular weight: 203.03 g/mol
• Formula: C₇H₇BrO₂
• Purity: Min. 95%
• InChI: InChI=1S/C7H7BrO2/c1-10-7-3-2-5(8)4-6(7)9/h2-4,9H,1H3
• InChI key: InChIKey=OLSJHVZRUFFIPL-UHFFFAOYSA-N
• SMILES: COc1ccc(Br)cc1O