3-Bromopyruvic acid hydrate
CAS: 206860-50-6
Ref. 3D-FB74926
1g | Discontinued | ||
5g | Discontinued | ||
10g | Discontinued |
Product Information
- Bromopyruvate
- Propanoic Acid, 3-Bromo-2-Oxo-, Ion(1-)
3-Bromopyruvic acid hydrate is a calcineurin inhibitor that has been shown to inhibit the production of inflammatory cytokines, such as TNF-α, IL-1β, and IL-6. 3-Bromopyruvic acid hydrate also inhibits the activation of nuclear factor kappa B (NF-κB) and inducible nitric oxide synthase (iNOS). It has been shown to be effective in the treatment of autoimmune disorders and organ transplant rejection. 3-Bromopyruvic acid hydrate is a macrocyclic compound, which is synthesized from three bromopyruvic acid molecules by joining them through their carboxyl groups. This compound binds to the calcineurin enzyme as a competitive inhibitor.