1-Benzothiophene-5-carboxylic acid

CAS: 2060-64-2

Ref. 3D-FB76002

Product Information

• Name: 1-Benzothiophene-5-carboxylic acid
• Synonyms: Benzothiophene-5-carboxylic acid, Benzo[b]thiophene-5-carboxylic acid

Description

1-Benzothiophene-5-carboxylic acid is an intermediate in the synthesis of a variety of heterocycles. It is used to synthesize indole and azidoacetate, which can be used for the synthesis of other compounds.

1-Benzothiophene-5-carboxylic acid is prepared by the reaction of ethyl azidoacetate with cyclohexanone followed by treatment with benzene in the presence of sodium hydroxide. The resultant product is hydrolyzed to 1-benzothiophene-5-carboxylic acid. The compound reacts with nitroethane and a base (e.g., potassium carbonate) to produce azidoacetate, which can be used as a precursor for other compounds.

• Brand: Biosynth

Chemical properties

• Molecular weight: 178.21 g/mol
• Formula: C₉H₆O₂S
• Purity: Min. 95%
• InChI: InChI=1S/C9H6O2S/c10-9(11)7-1-2-8-6(5-7)3-4-12-8/h1-5H,(H,10,11)
• InChI key: InChIKey=SNBYTKLWZRHESA-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccc2sccc2c1